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The Role of the UPR Pathway in the Pathophysiology and Treatment of Bipolar Disorder

31 Aug 2021

Abstract excerpt

Bipolar disorder (BD) is a mood disorder that affects millions worldwide and is associated with severe mood swings between mania and depression. The mood stabilizers valproate (VPA) and lithium (Li) are among the main drugs that are used to treat BD patients. However, these drugs are not effective for all patients and cause serious side effects. Therefore, better drugs are needed to treat BD patients. The main...

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PMID: 34531727
DOI: 10.3389/fncel.2021.735622

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