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Article

VDR Gene Polymorphisms and Cluster Headache Susceptibility: Case-Control Study in a Southeastern European Caucasian Population.

Journal of molecular neuroscience : MN - 1 Feb 2022

Papasavva Maria, Vikelis Michail, Siokas Vasileios, Katsarou Martha-Spyridoula, Dermitzakis Emmanouil, Raptis Athanasios, Dardiotis Efthimios, Drakoulis Nikolaos

Abstract excerpt

Cluster headache (CH) is a severe primary headache disorder with a genetic component, as indicated by family and twin studies. Diurnal and seasonal rhythmicity are key features of the disease and might be related to vitamin D, as low vitamin D levels have been observed in patients with cluster headache. In addition, the vitamin D receptor (VDR) occurs in brain areas and particularly in the hypothalamus. The aim...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34519950
DOI: 10.1007/s12031-021-01892-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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