Article
Genetic Variant Score and Arrhythmogenic Right Ventricular Cardiomyopathy Phenotype in Plakophilin-2 Mutation Carriers.
Cardiology - 1 Jan 2000
Svensson Anneli, Platonov Pyotr G, Haugaa Kristina H, Zareba Wojciech, Jensen Henrik Kjærulf, Bundgaard Henning, Gilljam Thomas, Madsen Trine, Hansen Jim, Dejgaard Lars A, Karlsson Lars O, Gréen Anna, Polonsky Bronislava, Edvardsen Thor, Svendsen Jesper Hastrup, Gunnarsson Cecilia
Abstract excerpt
INTRODUCTION: Whether detailed genetic information contributes to risk stratification of patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) remains uncertain. Pathogenic genetic variants in some genes seem to carry a higher risk for arrhythmia and earlier disease onset than others, but comparisons between variants in the same gene have not been done. Combined Annotation Dependent Depletion...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.