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Article

Family Screening in Relatives at Risk for Plakophilin-2-Associated Arrhythmogenic Right Ventricular Cardiomyopathy.

Circulation - 5 Aug 2025

Muller Steven A, Asatryan Babken, Gasperetti Alessio, Cramer Maarten J, Amin Ahmad S, Loh Peter, Carrick Richard T, Cox Moniek G P J, van der Harst Pim, Oerlemans Marish I F J, Tichnell Crystal, Yap Sing-Chien, Murray Brittney, Zimmerman Stefan L, van Tintelen J Peter, Calkins Hugh, Te Riele Anneline S J M, James Cynthia A

Abstract excerpt

BACKGROUND: Penetrance and risk of ventricular arrhythmias (VAs) in arrhythmogenic right ventricular cardiomyopathy (ARVC) are increasingly recognized as being genotype specific. Therefore, genotype-informed family screening protocols may lead to safer and more personalized recommendations than the current one-size-fits-all screening recommendations. We aimed to develop a safe, evidence-based plakophilin-2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40525281
DOI: 10.1161/CIRCULATIONAHA.125.074058
PMCID: PMC12240474

Genes

PKP2

Provenance

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