Article
Genetic predisposition to male breast cancer in Poland.
BMC cancer - 30 Aug 2021
Szwiec Marek, Tomiczek-Szwiec Joanna, Kluźniak Wojciech, Wokołorczyk Dominika, Osowiecka Karolina, Sibilski Robert, Wachowiak Małgorzata, Gronwald Jacek, Gronwald Helena, Lubiński Jan, Cybulski Cezary, Narod Steven A, Huzarski Tomasz
Abstract excerpt
BACKGROUND: Breast cancer in men accounts for fewer than 1 % of all breast cancer cases diagnosed in men and women. Genes which predispose to male breast cancer include BRCA1 and BRCA2. The role of other genes is less clear. In Poland, 20 founder mutations in BRCA1, BRCA2, CHEK2, PALB2, NBN, RECQL are responsible for the majority of hereditary breast cancer cases in women, but the utility this genes panel has not...
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