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Article

Genetic evaluation supports differential diagnosis in adolescent patients with delayed puberty.

European journal of endocrinology - 8 Oct 2021

Saengkaew Tansit, Patel Heena R, Banerjee Kausik, Butler Gary, Dattani Mehul T, McGuigan Michael, Storr Helen L, Willemsen Ruben H, Dunkel Leo, Howard Sasha R

Abstract excerpt

CONTEXT: Pubertal delay can be the clinical presentation of both idiopathic hypogonadotropic hypogonadism (IHH) and self-limited delayed puberty (SLDP). Distinction between these conditions is a common but important diagnostic challenge in adolescents. OBJECTIVE: To assess whether gene panel testing can assist with clinical differential diagnosis and to allow accurate and timely management of delayed puberty...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34403359
DOI: 10.1530/EJE-21-0387
PMCID: PMC8558847

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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