Small extracellular vesicles derived from in vivo‐ or in vitro‐produced bovine blastocysts have different miRNAs profiles—Implications for embryo‐maternal recognition

Abstract excerpt

In vivo- and in vitro-produced bovine embryos have different metabolic profiles and differences in gene transcription patterns. These embryos also have a distinct ability to establish and sustain early pregnancies. Small extracellular vesicles (sEVs) are secreted by embryos and carry bioactive molecules, such as miRNAs. We hypothesize that in vivo or in vitro-produced bovine hatched blastocysts on Day 9 and the...

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