Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of ISM1 on the Immune Microenvironment and Epithelial-Mesenchymal Transition in Colorectal Cancer

19 Jul 2021

Abstract excerpt

Background: An increasing number of studies have shown that Isthmin 1 (ISM1), a secreted protein, is important in tumorigenesis and invasion, including in colorectal cancer (CRC). However, the mechanisms are still unclear. This study aims to explore the function and prognosis capacity of ISM1 in CRC. Methods: We investigated the expression of ISM1 in 18 CRC tissues vs. adjacent normal tissues from GSE50760, 473...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Ferroptosis and cancer prognosis
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34350177
DOI: 10.3389/fcell.2021.681240

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of ISM1 on the Immune Microenvironment and Epithelial-Mesenchymal Transition in Colorectal CancerPMID 34350177Read ↗

MTUS1 is Correlated with Immune Infiltration and Acts as a Promising Diagnostic and Prognostic Biomarker for Colorectal Cancer.Semantic proximity Read ↗

SLC11A1 associated with tumor microenvironment is a potential biomarker of prognosis and immunotherapy efficacy for colorectal cancerSemantic proximity Read ↗

CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3Semantic proximity Read ↗

CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3Semantic proximity Read ↗

Long Non-coding RNA ITIH4-AS1 Accelerates the Proliferation and Metastasis of Colorectal Cancer by Activating JAK/STAT3 SignalingSemantic proximity Read ↗

<i>TWIST1</i> mediated transcriptional activation of <i>SPON2</i> drives colorectal peritoneal metastasis through activation of cancer-associated fibroblast signaling networkSemantic proximity Read ↗

Follistatin-Like 3 Correlates With Lymph Node Metastasis and Serves as a Biomarker of Extracellular Matrix Remodeling in Colorectal CancerSemantic proximity Read ↗

IL-1R signaling drives enteric glia-macrophage interactions in colorectal cancerSemantic proximity Read ↗

Clinical value of FAT1 mutations to indicate the immune response in colorectal cancer patients.Semantic proximity Read ↗

STAT1 as a potential prognosis marker for poor outcomes of early stage colorectal cancer with microsatellite instabilitySemantic proximity Read ↗

Expression of ISG15 in colorectal cancer and exploration of its mechanism of actionSemantic proximity Read ↗

Long non-coding RNA SPRY4-IT1 pormotes colorectal cancer metastasis by regulate epithelial-mesenchymal transitionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.