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Article

S100A8 may govern hyper-inflammation in severe COVID-19.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Sept 2021

Deguchi Atsuko, Yamamoto Tomoko, Shibata Noriyuki, Maru Yoshiro

Abstract excerpt

The coronavirus disease 2019 (COVID-19) pandemic threatens human species with mortality rate of roughly 2%. We can hardly predict the time of herd immunity against and end of COVID-19 with or without success of vaccine. One way to overcome the situation is to define what delineates disease severity and serves as a molecular target. The most successful analogy is found in BCR-ABL in chronic myeloid leukemia, which...

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PMID: 34339064
DOI: 10.1096/fj.202101013
PMCID: PMC8441709

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