Article
Full Genomic Sequences of H5N1 Highly Pathogenic Avian Influenza Virus in Human Autopsy Specimens Reveal Genetic Variability and Adaptive Changes for Growth in MDCK Cell Cultures.
BioMed research international - 1 Jan 2021
Sangsiriwut Kantima, Noisumdaeng Pirom, Uiprasertkul Mongkol, Prasertsopon Jarunee, Payungporn Sunchai, Auewarakul Prasert, Ungchusak Kumnuan, Puthavathana Pilaipan
Abstract excerpt
The entire H5N1 highly pathogenic avian influenza viral genomes were identified in the frozen autopsy specimens: the trachea, lung, colon, and intestinal feces from a patient who died of the disease in 2006. Phylogenetic analysis of the viral genomes showed that these viruses belonged to clade 1 and were the reassortants generated from the reassortment of the viruses within the same clade. The sequencing data...
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