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MRI-Based Radiomics Nomogram as a Potential Biomarker to Predict the EGFR Mutations in Exon 19 and 21 Based on Thoracic Spinal Metastases in Lung Adenocarcinoma.

Academic radiology - 1 Mar 2022

Cao Ran, Dong Yue, Wang Xiaoyu, Ren Meihong, Wang Xingling, Zhao Nannan, Yu Tao, Zhang Lu, Luo Yahong, Cui E-Nuo, Jiang Xiran

Abstract excerpt

RATIONALE AND OBJECTIVES: Preoperative identifications of epidermal growth factor receptor (EGFR) mutation subtypes based on the MRI image of spinal metastases are needed to provide individualized therapy, but has not been previously investigated. This study aims to develop and evaluate an MRI-based radiomics nomogram for differentiating the exon 19 and 21 in EGFR mutation from spinal bone metastases in patients...

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PMID: 34332860
DOI: 10.1016/j.acra.2021.06.004

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