Article
The Chicken Pan-Genome Reveals Gene Content Variation and a Promoter Region Deletion in IGF2BP1 Affecting Body Size.
Molecular biology and evolution - 27 Oct 2021
Wang Kejun, Hu Haifei, Tian Yadong, Li Jingyi, Scheben Armin, Zhang Chenxi, Li Yiyi, Wu Junfeng, Yang Lan, Fan Xuewei, Sun Guirong, Li Donghua, Zhang Yanhua, Han Ruili, Jiang Ruirui, Huang Hetian, Yan Fengbin, Wang Yanbin, Li Zhuanjian, Li Guoxi, Liu Xiaojun, Li Wenting, Edwards David, Kang Xiangtao
Abstract excerpt
Domestication and breeding have reshaped the genomic architecture of chicken, but the retention and loss of genomic elements during these evolutionary processes remain unclear. We present the first chicken pan-genome constructed using 664 individuals, which identified an additional approximately 66.5-Mb sequences that are absent from the reference genome (GRCg6a). The constructed pan-genome encoded 20,491...
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