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SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts.

PloS one - 1 Jan 2021

Tasakis Rafail Nikolaos, Samaras Georgios, Jamison Anna, Lee Michelle, Paulus Alexandra, Whitehouse Gabrielle, Verkoczy Laurent, Papavasiliou F Nina, Diaz Marilyn

Abstract excerpt

Since the first case of COVID-19 in December 2019 in Wuhan, China, SARS-CoV-2 has spread worldwide and within a year and a half has caused 3.56 million deaths globally. With dramatically increasing infection numbers, and the arrival of new variants with increased infectivity, tracking the evolution of its genome is crucial for effectively controlling the pandemic and informing vaccine platform development. Our...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34297786
DOI: 10.1371/journal.pone.0255169
PMCID: PMC8301627

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