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Article

Genome-wide DNA (hydroxy) methylation reveals the individual epigenetic landscape importance on osteogenic phenotype acquisition in periodontal ligament cells.

Journal of periodontology - 1 Mar 2022

Ferreira Rogério S, Assis Rahyza I F, Feltran Geórgia da S, do Rosário Palma Iasmin Caroline, Françoso Beatriz G, Zambuzzi Willian F, Andia Denise C, da Silva Rodrigo A

Abstract excerpt

BACKGROUND: Mesenchymal cells' biology has been an important investigative tool to maximize bone regeneration through tissue engineering. Here we used mesenchymal cells from periodontal ligament (PDLCs) with high (h-) and low (l-) osteogenic potential, isolated from different donors, to investigate the impact of the individual epigenetic and transcriptional profiles on the osteogenic potential. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34291826
DOI: 10.1002/JPER.21-0218

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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