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Article

TRIM27 interacts with Iκbα to promote the growth of human renal cancer cells through regulating the NF-κB pathway

20 Jul 2021

Abstract excerpt

BACKGROUND: The tripartite motif (TRIM) family proteins exhibit oncogenic roles in various cancers. The roles of TRIM27, a member of the TRIM super family, in renal cell carcinoma (RCC) remained unexplored. In the current study, we aimed to investigate the clinical impact and roles of TRIM27 in the development of RCC. METHODS: The mRNA levels of TRIM27 and Kaplan-Meier survival of RCC were analyzed from The...

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PMID: 34284744
DOI: 10.1186/s12885-021-08562-5

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