Article
A spectral theory for Wright's inbreeding coefficients and related quantities.
PLoS genetics - 1 Jul 2021
François Olivier, Gain Clément
Abstract excerpt
Wright's inbreeding coefficient, FST, is a fundamental measure in population genetics. Assuming a predefined population subdivision, this statistic is classically used to evaluate population structure at a given genomic locus. With large numbers of loci, unsupervised approaches such as principal component analysis (PCA) have, however, become prominent in recent analyses of population structure. In this study, we...
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