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Genetic Diversity and Azole Resistance Among Natural Aspergillus fumigatus Populations in Yunnan, China.

Microbial ecology - 1 May 2022

Zhou Duanyong, Wang Ruirui, Li Xiao, Peng Bin, Yang Guangzhu, Zhang Ke-Qin, Zhang Ying, Xu Jianping

Abstract excerpt

The emergence and spread of azole resistance alleles in clinical and environmental isolates of Aspergillus fumigatus is a global human health concern and endangers the "One Health" approach in our fight against antifungal resistance (AFR) in this pathogen. A major challenge to combat AFR in A. fumigatus is the massive aerial dispersal ability of its asexual spores. Our recent fine-scale survey of greenhouse...

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PMID: 34279697
DOI: 10.1007/s00248-021-01804-w

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