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Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approaches

24 Mar 2021

Abstract excerpt

During the course of a viral infection, virus-host protein-protein interactions (PPIs) play a critical role in allowing viruses to replicate and survive within the host. These interspecies molecular interactions can lead to viral-mediated perturbations of the human interactome causing the generation of various complex diseases. Evidences suggest that viral-mediated perturbations are a possible pathogenic etiology...

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PMID: 34237135
DOI: 10.1093/bib/bbab141

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