Gastrointestinal Chlamydia-Induced CD8 + T Cells Promote Chlamydial Pathogenicity in the Female Upper Genital Tract

Abstract excerpt

T cells induced by gastrointestinal Chlamydia are both necessary and sufficient for promoting hydrosalpinx in the genital tract. The study has laid a foundation for further revealing the mechanisms by which Chlamydia-induced T lymphocyte responses (as a 2nd hit) promote hydrosalpinx in mice with genital Chlamydia-triggered tubal injury (as a 1st hit), a continuing effort in testing the two-hit hypothesis as a...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genital Health and Disease
• Share to Pelvic floor disorders treatments
• Share to Reproductive tract infections research