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Article

Abnormal expression and methylation of PRR34-AS1 are associated with adverse outcomes in acute myeloid leukemia.

Cancer medicine - 1 Aug 2021

Nan Fang-Yu, Gu Yu, Xu Zi-Jun, Sun Guo-Kang, Zhou Jing-Dong, Zhang Ting-Juan, Ma Ji-Chun, Leng Jia-Yan, Lin Jiang, Qian Jun

Abstract excerpt

It was previously reported that PRR34-AS1 was overexpressed in some solid tumors. PRR34-AS1 promoter was shown to have a differential methylation region (DMR), and was hypomethylated in acute myeloid leukemia (AML). Therefore, the present study used real-time quantitative PCR (RQ-PCR) to explore the expression characteristics of PRR34-AS1 in AML. In addition, the correlation between the expression of PRR34-AS1...

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Multivariate Analysis

Share to Neoplasm Proteins

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Share to Promoter Regions, Genetic

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Identifiers

PMID: 34227248
DOI: 10.1002/cam4.4085
PMCID: PMC8335806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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