Article
Kinase Inhibitors in the Treatment of Thyroid Cancer: Institutional Experience.
Acta clinica Croatica - 1 Jun 2020
Pešorda Matea, Kusačić Kuna Sanja, Huić Dražen, Herceg Davorin, Despot Marija, Samardžić Tatjana, Gnjidić Milena, Belev Borislav
Abstract excerpt
Although most patients with thyroid cancer have a favorable clinical course, some patients develop a more aggressive type of cancer and exhibit more rapid disease progression with worse prognosis. Those patients usually exhibit mutations of proteins such as tyrosine kinase enzymes that play a significant role in regulation of tumor proliferation and spreading. Development of targeted therapies is based on the...
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