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Reliability of Tumor Testing Compared to Germline Testing for Detecting BRCA1 and BRCA2 Mutations in Patients with Epithelial Ovarian Cancer

24 Jun 2021

Abstract excerpt

BACKGROUND: BRCA 1/2 mutation status has become one of the most important parameters for treatment decision in patients with epithelial ovarian cancer (EOC). The aim of this study was to compare tumor DNA with blood DNA sequencing to evaluate the reliability of BRCA tumor testing results. METHODS: Patients who were treated for EOC between 2003 and 2019 at the Medical University of Vienna and underwent both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34202525
DOI: 10.3390/jpm11070593

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