Article
Diagnostic Accuracy of Serum Hyaluronan for Detecting HCV Infection and Liver Fibrosis in Asymptomatic Blood Donors.
Molecules (Basel, Switzerland) - 25 Jun 2021
Rodart Itatiana F, Pares Madalena M, Mendes Aline, Accardo Camila M, Martins João R M, Silva Cleidenice B, Carvalho Fabrício O, Barreto José A, Reis Mitermayer G, Tersariol Ivarne L S, Nader Helena B
Abstract excerpt
Background: The disease caused by hepatitis C virus (HCV) is asymptomatic, silent, and progressive liver disease. In HCV-infected patients the increase in serum HA is associated with the development of hepatic fibrosis and disease progression. Methods: HCV-RNA detection was performed in all serological samples of blood donors that tested positive using HCV Ultra ELISA. Determination of hyaluronan (HA) was...
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