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Smoking, alcohol and coffee consumption and pregnancy loss: a Mendelian randomization investigation.

Fertility and sterility - 1 Oct 2021

Yuan Shuai, Liu Jin, Larsson Susanna C

Abstract excerpt

OBJECTIVE: To determine the associations of smoking and alcohol and coffee consumption with pregnancy loss. DESIGN: Mendelian randomization study. SETTING: The UK Biobank study and FinnGen consortium. PATIENTS: A total of 60,565 cases with pregnancy loss and 130,687 noncases from UK Biobank and 3,312 cases with pregnancy loss and 64,578 noncases from FinnGen. INTERVENTION(S): None. MAINS OUTCOME MEASURE:...

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PMID: 34187701
DOI: 10.1016/j.fertnstert.2021.05.103

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