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Sarcopenia and preserved bone mineral density in paediatric survivors of high‐risk neuroblastoma with growth failure

29 Jun 2021

Abstract excerpt

BACKGROUND: Survival from paediatric high-risk neuroblastoma (HR-NBL) has increased, but cis-retinoic acid (cis-RA), the cornerstone of HR-NBL therapy, can cause osteoporosis and premature physeal closure and is a potential threat to skeletal structure in HR-NBL survivors. Sarcopenia is associated with increased morbidity in survivors of paediatric malignancies. Low muscle mass may be associated with poor...

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PMID: 34184837
DOI: 10.1002/jcsm.12734

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