In silico trio biomarkers for bacterial vaginosis revealed by species dominance network analysis

Abstract excerpt

BV (bacterial vaginosis) influences 20%–40% of women but its etiology is still poorly understood. An open question about BV is which of the hundreds of bacteria found in the human vaginal microbiome (HVM) are the major force driving the vaginal microbiota dysbiosis. Here, we recast the question of microbial causality of BV by asking if there are any prevalent ‘signatures’ (network motifs) in the vaginal...

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