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Anaerobic Microbiota Derived from the Upper Airways Impact Staphylococcus aureus Physiology

14 Jun 2021

Abstract excerpt

, and Streptococcus comprised a core mucin-degrading community across CRS subjects that generated a nutrient pool that augmented S. aureus growth on mucin as a carbon source. Finally, using transcriptome sequencing (RNA-seq), we observed that S. aureus transcription is profoundly altered in the presence of mucin-derived metabolites, though expression of several key metabolism- and virulence-associated pathways...

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PMID: 34125598
DOI: 10.1128/iai.00153-21

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