Article
18F-THK5351 PET Can Identify Core Lesions in Different Amyotrophic Lateral Sclerosis Phenotypes.
Clinical nuclear medicine - 1 Dec 2021
Higashihara Mana, Ishibashi Kenji, Tokumaru Aya M, Iwata Atsushi, Ishii Kenji
Abstract excerpt
ABSTRACT: Two patients with different amyotrophic lateral sclerosis (ALS) phenotypes underwent 18F-THK5351 PET to visualize lesions undergoing astrogliosis by measuring monoamine oxidase B activity. Patient 1 was a 57-year-old man with flail leg syndrome. Elevated uptake was observed inside the motor cortex, corresponding to the leg area in a cortical homunculus. Patient 2 was a 64-year-old man with...
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