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LncRNA CTD-2528L19.6 prevents the progression of IPF by alleviating fibroblast activation

10 Jun 2021

Abstract excerpt

Long non-coding RNAs (lncRNAs) have emerged as critical factors for regulating multiple biological processes during organ fibrosis. However, the mechanism of lncRNAs in idiopathic pulmonary fibrosis (IPF) remains incompletely understood. In the present study, two sets of lncRNAs were defined: IPF pathogenic lncRNAs and IPF progression lncRNAs. IPF pathogenic and progression lncRNAs-mRNAs co-expression networks...

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PMID: 34112765
DOI: 10.1038/s41419-021-03884-5

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