Article
PID1 is associated to a respiratory endotype related to occupational exposures to irritants.
Free radical biology & medicine - 20 Aug 2021
Andrianjafimasy Miora, Orsi Laurent, Margaritte-Jeannin Patricia, Mohamdi Hamida, Demenais Florence, Le Moual Nicole, Matran Regis, Zerimech Farid, Dumas Orianne, Dizier Marie-Hélène, Nadif Rachel
Abstract excerpt
BACKGROUND: Studying associations between genes and asthma endotypes and interactions with environment could help to identify new susceptibility genes. We used a previously identified asthma endotype characterized by adult-onset asthma, poor lung function, and high level of Fluorescent oxidation products, a marker of damages due to oxidative stress. This endotype was associated with high occupational exposure to...
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