Article
[EGFR protein is a negative prognostic and predictive factor in wild-type RAS colorectal cancer].
Magyar onkologia - 3 Jun 2021
Uhlyarik Andrea, Piurkó Violetta, Pápai Zsuzsanna, Rásó Erzsébet, Lahm Erika, Kiss Edina, Sikter Márta, Vachaja József, Vízkeleti Laura, Kenessey István, Tímár József
Abstract excerpt
Negative predictive markers of the anti-EGFR antibody therapies are RAS or BRAF mutations, while left sidedness can be considered as a positive predictor. Here we analyzed 97 wild type RAS metastatic colorectal cancers looking for the prognostic and predictive roles of EGFR protein expression. We found that right-sided colorectal cancers are characterized by significantly higher EGFR protein expression as...
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