The Influence of rs1859168 Polymorphism on Serum Expression of HOTTIP and Its Target miR-615-3p in Egyptian Patients with Breast Cancer.

doi:10.3390/biom11050733

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The Influence of rs1859168 Polymorphism on Serum Expression of HOTTIP and Its Target miR-615-3p in Egyptian Patients with Breast Cancer.

Biomolecules - 14 May 2021

Abdelaleem Omayma O, Shaker Olfat G, AbdelHafez Marwa N, Abdelghaffar Noha K, Eid Hanaa M, Zaidan Mohamed, Khalefa Abeer A, Ahmed Naglaa A, Hemeda Nada F, Zaki Othman M, Awaji Aeshah Ali A, Mohammed Shereen R

Abstract excerpt

BACKGROUND: Polymorphisms of long noncoding RNAs are lately documented as hazardous factors for the development of numerous tumors. Furthermore, the evaluation of noncoding RNAs has emerged as a novel detector of breast cancer patients. We aimed to genotype the HOXA transcript at the distal tip (HOTTIP) rs1859168 and assess its relationship with the levels of the serum HOTTIP and its target miR-615-3p in patients...

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PMID: 34069089
DOI: 10.3390/biom11050733
PMCID: PMC8156858

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