Article
Potential of Intestinal Current Measurement for Personalized Treatment of Patients with Cystic Fibrosis
8 May 2021
Abstract excerpt
Refinement of personalized treatment of cystic fibrosis (CF) with emerging medicines targeting the CF basic defect will likely benefit from biomarkers sensitive to detect improvement of cystic fibrosis transmembrane conductance regulator (CFTR) function in individual patients. Intestinal current measurement (ICM) is a technique that enables quantitative assessment of CFTR chloride channel function in rectal...
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