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Multiplex PCR-Based Nanopore Sequencing and Epidemiological Surveillance of Hantaan orthohantavirus in Apodemus agrarius, Republic of Korea.

Viruses - 6 May 2021

Park Kyungmin, Lee Seung-Ho, Kim Jongwoo, Lee Jingyeong, Lee Geum-Young, Cho Seungchan, Lee Seung Ho, Park Kkothanahreum, No Jin Sun, Budhathoki Shailesh, Kim Yu-Jin, Kim Young-Su, Kim Heung-Chul, Klein Terry A, Kim Won-Keun, Song Jin-Won

Abstract excerpt

Whole-genome sequencing of infectious agents enables the identification and characterization of emerging viruses. The MinION device is a portable sequencer that allows real-time sequencing in fields or hospitals. Hantaan orthohantavirus (Hantaan virus, HTNV), harbored by Apodemus agrarius, causes hemorrhagic fever with renal syndrome (HFRS) and poses a critical public health threat worldwide. In this study, we...

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PMID: 34066592
DOI: 10.3390/v13050847
PMCID: PMC8148566

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