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B Cells and Microbiota in Autoimmunity

3 May 2021

Abstract excerpt

Trillions of microorganisms inhabit the mucosal membranes maintaining a symbiotic relationship with the host's immune system. B cells are key players in this relationship because activated and differentiated B cells produce secretory immunoglobulin A (sIgA), which binds commensals to preserve a healthy microbial ecosystem. Mounting evidence shows that changes in the function and composition of the gut microbiota...

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PMID: 34063669
DOI: 10.3390/ijms22094846

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