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Heterogeneity of Colorectal Cancer Progression: Molecular Gas and Brakes

15 May 2021

Abstract excerpt

The review begins with molecular genetics, which hit the field unveiling the involvement of oncogenes and tumor suppressor genes in the pathogenesis of colorectal cancer (CRC) and uncovering genetic predispositions. Then the notion of molecular phenotypes with different clinical behaviors was introduced and translated in the clinical arena, paving the way to next-generation sequencing that captured previously...

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PMID: 34063506
DOI: 10.3390/ijms22105246

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