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Article

Circulating ceramides as biomarkers of cardiovascular disease: Evidence from phenotypic and genomic studies

6 May 2021

Abstract excerpt

There is a need for new biomarkers of atherosclerotic cardiovascular disease (ACVD), the main cause of death globally. Ceramides, a class of potent bioactive lipid mediators, have signalling roles in apoptosis, cellular stress and inflammation. Recent studies have highlighted circulating ceramides as novel biomarkers of coronary artery disease, type-2 diabetes and insulin resistance. Ceramides are highly...

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Share to Cholesterol and Lipid Metabolism
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PMID: 34004484
DOI: 10.1016/j.atherosclerosis.2021.04.021

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