Draft genome sequence of a carbapenemase-producing (NDM-1) and multidrug-resistant, hypervirulent Klebsiella pneumoniae ST11 isolate from Pakistan, with a non-hypermucoviscous phenotype associated with rmpA2 mutation.

Abstract excerpt

OBJECTIVES: ST11 is a high-risk sequence type associated with carbapenem-resistant Klebsiella pneumoniae strains. Carbapenemase-producing hypervirulent K. pneumoniae (hvKp) are a major concern as they harbour a diverse range of pathogenicity traits. Here we describe the characteristics of K. pneumoniae strain KP75w isolated from a tertiary-care hospital in Pakistan. METHODS: Antimicrobial susceptibility testing...

Topics

• Bacterial Proteins
• Humans
• Klebsiella Infections
• Klebsiella pneumoniae
• Multilocus Sequence Typing
• Mutation
• Pakistan
• Phenotype
• beta-Lactamases