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Tape stripping and lipidomics reveal skin surface lipid abnormity in female melasma

11 May 2021

Abstract excerpt

The skin barrier of melasma is involved in the pathogenesis of melasma. Previous studies have shown that there are differences in the expression of epidermal lipid genes in melasma, but little is known about the epidermis lipid composition of melasma. Compared with the non-lesional skin, the content of total lipids, phosphatidic acid, phosphatidylserine, and ceramide (Cer) increased significantly in the lesional...

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PMID: 33974351
DOI: 10.1111/pcmr.12984

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