Article
Genetic and immunologic findings in children with recurrent aphthous stomatitis with systemic inflammation.
Pediatric rheumatology online journal - 10 May 2021
Girardelli Martina, Valencic Erica, Moressa Valentina, Margagliotta Roberta, Tesser Alessandra, Pastore Serena, Spadola Ottavia, Athanasakis Emmanouil, Severini Giovanni Maria, Taddio Andrea, Tommasini Alberto
Abstract excerpt
BACKGROUND: Recurrent aphthous stomatitis with systemic signs of inflammation can be encountered in inflammatory bowel disease, Behçet's disease (BD), Systemic Lupus Erythematosus (SLE). In addition, it has been proposed that cases with very early onset in childhood can be underpinned by rare monogenic defects of immunity, which may require targeted treatments. Thus, subjects with early onset recurrent aphthous...
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