Article
[Expression of COL9A1 gene and its polymorphism in children with idiopathic congenital talipes equinovarus].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 1 Jun 2011
Liu Li-Ying, Jin Chun-Lian, Jiang Li, Lin Chang-Kun
Abstract excerpt
OBJECTIVE: COL9A1 gene is located in the susceptibility region of idiopathic congenital talipes equinovarus (ICTEV) (6q12-13). This study aimed to investigate the expression of the COL9A1 gene and the distribution of single nucleotide polymorphism (SNP) of COL9A1 gene in patients with ICTEV and normal controls. METHODS: Immunohistochemistry was used to detect the expression of COL9A1 in 25 children with ICTEV and...
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