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Longitudinal virological changes and underlying pathogenesis in hospitalized COVID-19 patients in Guangzhou, China.

Science China. Life sciences - 1 Dec 2021

Li Zhengtu, Li Yinhu, Sun Ruilin, Li Shaoqiang, Chen Lingdan, Zhan Yangqing, Xie Mingzhou, Yang Jiasheng, Wang Yanqun, Zhu Airu, Gu Guoping, Yu Le, Li Shuaicheng, Liu Tingting, Chen Zhaoming, Jian Wenhua, Jiang Qian, Su Xiaofen, Gu Weili, Chen Liyan, Cheng Jing, Zhao Jincun, Lu Wenju, Zheng Jinping, Li Shiyue, Zhong Nanshan, Ye Feng

Abstract excerpt

Prolonged viral RNA shedding and recurrence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in coronavirus disease 2019 (COVID-19) patients have been reported. However, the clinical outcome and pathogenesis remain unclear. In this study, we recruited 43 laboratory-confirmed COVID-19 patients. We found that prolonged viral RNA shedding or recurrence mainly occurred in severe/critical patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33945070
DOI: 10.1007/s11427-020-1921-5
PMCID: PMC8093132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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