Article
Is there a role for doravirine in African HIV treatment programmes? A large observational resistance study in South Africa.
Journal of the International AIDS Society - 1 May 2021
Steegen Kim, Moorhouse Michelle, Wensing Annemarie Mj, Venter Willem Df, Hans Lucia
Abstract excerpt
INTRODUCTION: Dolutegravir has replaced efavirenz in most low- and middle-income countries, due to better tolerability and formidable resistance profile, but dolutegravir side effects suggest alternatives are needed. We evaluated doravirine resistance in South Africa as a first step to assess whether doravirine may replace dolutegravir. METHODS: A retrospective dataset was analysed for predicted doravirine...
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