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Article

Genome sequencing of SARS-CoV-2 in a cohort of Egyptian patients revealed mutation hotspots that are related to clinical outcomes.

Biochimica et biophysica acta. Molecular basis of disease - 1 Aug 2021

Zekri Abdel-Rahman N, Mohanad Marwa, Hafez Mohammed M, Soliman Hany K, Hassan Zainab K, Abouelhoda Mohamed, Amer Khaled E, Seadawy Mohamed G, Ahmed Ola S

Abstract excerpt

BACKGROUND: Severe acute respiratory syndrome-2 (SARS-CoV-2) exhibits a broad spectrum of clinical manifestations. Despite the fact that SARS-CoV-2 has slower evolutionary rate than other coronaviruses, different mutational hotspots have been identified along the SARS-CoV-2 genome. METHODS: We performed whole-genome high throughput sequencing on isolates from 50 Egyptian patients to see if the variation in...

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Identifiers

PMID: 33932525
DOI: 10.1016/j.bbadis.2021.166154
PMCID: PMC8079944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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