Article
Knock out of specific maternal vitellogenins in zebrafish (Danio rerio) evokes vital changes in egg proteomic profiles that resemble the phenotype of poor quality eggs.
BMC genomics - 28 Apr 2021
Yilmaz Ozlem, Patinote Amelie, Com Emmanuelle, Pineau Charles, Bobe Julien
Abstract excerpt
BACKGROUND: We previously reported the results of CRISPR/Cas9 knock-out (KO) of type-I and type-III vitellogenins (Vtgs) in zebrafish, which provided the first experimental evidence on essentiality and disparate functioning of Vtgs at different stages during early development. However, the specific contributions of different types of Vtg to major cellular processes remained to be investigated. The present study...
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