How autophagy controls the intestinal epithelial barrier.

doi:10.1080/15548627.2021.1909406

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Article

How autophagy controls the intestinal epithelial barrier.

Autophagy - 1 Jan 2022

Foerster Elisabeth G, Mukherjee Tapas, Cabral-Fernandes Liliane, Rocha Juliana D B, Girardin Stephen E, Philpott Dana J

Abstract excerpt

Macroautophagy/autophagy is a cellular catabolic process that results in lysosome-mediated recycling of organelles and protein aggregates, as well as the destruction of intracellular pathogens. Its role in the maintenance of the intestinal epithelium is of particular interest, as several autophagy-related genes have been associated with intestinal disease. Autophagy and its regulatory mechanisms are involved in...

Topics

Animals
Mice
Autophagy
Autophagy-Related Proteins
Beclin-1
Escherichia coli
Interferons
Intestines
Leucine
Mechanistic Target of Rapamycin Complex 1
Phosphatidylinositol 3-Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phosphatidylinositols

Prokaryotic Initiation Factor-2

Proline

Protein Serine-Threonine Kinases

Sirolimus

Trans-Activators

Transcription Factors

Source

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Identifiers

PMID: 33906557
DOI: 10.1080/15548627.2021.1909406
PMCID: PMC8865220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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