Article
Monoclonal antibodies specific for the hemagglutinin-neuraminidase protein define neutralizing epitopes specific for Newcastle disease virus genotype 2.VII from Egypt.
Virology journal - 26 Apr 2021
Moharam Ibrahim, Asala Olayinka, Reiche Sven, Hafez Hafez, Beer Martin, Harder Timm, Grund Christian
Abstract excerpt
BACKGROUND: Newcastle disease is a devastating disease in poultry caused by virulent Newcastle disease virus (NDV), a paramyxovirus endemic in many regions of the world despite intensive vaccination. Phylogenetic analyses reveal ongoing evolution of the predominant circulating genotype 2.VII, and the relevance of potential antigenic drift is under discussion. To investigate variation within...
Topics
- Animals
- Antibodies, Monoclonal
- Antigenic Drift and Shift
- Chickens
- Egypt
- Epitopes
- Genotype
- HN Protein
- Mice
- Mice, Inbred BALB C
- Newcastle Disease