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Article

Clinical Outcome and Striatal Dopaminergic Function After Shunt Surgery in Patients With Idiopathic Normal Pressure Hydrocephalus.

Neurology - 8 Jun 2021

Todisco Massimiliano, Zangaglia Roberta, Minafra Brigida, Pisano Patrizia, Trifirò Giuseppe, Bossert Irene, Pozzi Nicoló Gabriele, Brumberg Joachim, Ceravolo Roberto, Isaias Ioannis Ugo, Fasano Alfonso, Pacchetti Claudio

Abstract excerpt

OBJECTIVE: To determine changes in clinical features and striatal dopamine reuptake transporter (DAT) density after shunt surgery in patients with idiopathic normal pressure hydrocephalus (iNPH). METHODS: Participants with probable iNPH were assessed at baseline by means of clinical rating scales, brain MRI, and SPECT with [123I]-N-ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane (FP-CIT). Levodopa...

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Identifiers

PMID: 33893195
DOI: 10.1212/WNL.0000000000012064
PMCID: PMC8205459

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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