Article
Conditional destabilization of the TPLATE complex impairs endocytic internalization.
Proceedings of the National Academy of Sciences of the United States of America - 13 Apr 2021
Wang Jie, Yperman Klaas, Grones Peter, Jiang Qihang, Dragwidge Jonathan, Mylle Evelien, Mor Eliana, Nolf Jonah, Eeckhout Dominique, De Jaeger Geert, De Rybel Bert, Pleskot Roman, Van Damme Daniel
Abstract excerpt
In plants, endocytosis is essential for many developmental and physiological processes, including regulation of growth and development, hormone perception, nutrient uptake, and defense against pathogens. Our toolbox to modulate this process is, however, rather limited. Here, we report a conditional tool to impair endocytosis. We generated a partially functional TPLATE allele by substituting the most conserved...
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