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Article

Studying models of balancing selection using phase-type theory.

Genetics - 24 Jun 2021

Zeng Kai, Charlesworth Brian, Hobolth Asger

Abstract excerpt

Balancing selection (BLS) is the evolutionary force that maintains high levels of genetic variability in many important genes. To further our understanding of its evolutionary significance, we analyze models with BLS acting on a biallelic locus: an equilibrium model with long-term BLS, a model with long-term BLS and recent changes in population size, and a model of recent BLS. Using phase-type theory, a...

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Identifiers

PMID: 33871627
DOI: 10.1093/genetics/iyab055
PMCID: PMC8225346

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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